It's going to be an adjustment period for Creighton. They've scheduled like a mid major in recent years (not a diss - when you're a mid major, you schedule like a mid major ). Now they're going to a conference where they'll be expected to schedule like a big boy. They're going into a conference with a culture of buy games, just a couple of true road games, if any, and the marquee game or three at home or on a neutral court on national TV.
Creighton might actually be frowned upon by the rest of their league if they have a couple home-and-home series with MVC schools on the schedule. Creighton in the past few years have had series (both home and away) with CUSA and A-10 schools too I think. The dirty secret about some of these schools in the C7 is that they don't go on the road much, so I wonder how many of these would continue.
All that said, Creighton/Wichita is the one obvious game that would look good in the Big East's eyes. So I'd work on making that a home-and-home series for the foreseeable future. I think that's a game that can be marketed to FOX for a prime non-conference time slot.